For example: Kif23, a molecular motor, has been shown to regulate the distribution of microtubules differentially into axons and dendrites in cultured rat superior cervical ganglia (SCG) neurons, thereby modulating the rate of axon versus dendrite outgrowth;49–51 Tpx, a microtubule-associated protein has been shown to be required for neurite elongation in mouse hippocampal neurons and rat SCG neurons;52,53 E2f1 and Chek1 are modulators of neuron survival and cell cycle;54–56 Bcas1, myelination associated protein, which has been linked with schizophrenia-like behavior abnormality57. The gene discussed is E2F1; the disease is schizophrenia.