Thus, compared to RA patients sharing the CG/GG genotype, those with the CC genotype of the rs2073618 OPG variant were found to display increased rates of RF positivity and higher IMT values (69.9 vs 55.1, p = 0.02 and 0.872 ± 0.264 vs 0.816 ± 0.284, p = 0.01, respectively). This evidence concerns the gene TNFRSF11B and rheumatoid arthritis.