Another large study evaluating 12 SNPs in RA patients, identified novel associations between subclinical atherosclerosis and variants in SLC17A2 (rs17526722), PPCDC (rs1867148), COL4A1 (rs496916) and SLCA13 (rs515291) genes, that may constitute new candidate risk loci for CVD in RA89. This evidence concerns the gene PPCDC and rheumatoid arthritis.