Thus, ANXA1 overexpression ameliorated kidney injuries, albuminuria, glomerulosclerosis, tubulointerstitial fibrosis, and kidney inflammation by inhibiting NF-κB signaling.235 The consistent results were obtained from ANXA1 mimetic peptide, Ac2-26 treated diabetic kidney disease mice. Here, NFKB1 is linked to glomerulosclerosis.