CHI3L1 and chronic kidney disease: The relationship between inflammatory factors and the progression of CKD was assessed after a median of 4.3 years of follow-up.304 The results showed MCP-1/CCL2 and YKL-40 (CHI3L1) levels were negatively associated with eGFR, and uromodulin (UMOD) level was positively associated with eGFR.