AURKB and breast cancer: When Aurora B kinase is inhibited, the cytoplasm of the cell cannot be divided and cell growth is arrested.281 Since both Aurora A and Aurora B kinases are related to tumorigenesis, Aurora kinase inhibitors have been extensively carried out in clinical researches on various diseases, such as lung cancer, breast cancer, esophageal cancer, colorectal cancer, acute myeloid leukemia and so on, but currently no drugs have been approved for clinical use.