Several key growth factors, such as hepatocyte growth factor (HGF), epithelial growth factor (EGF), vascular endothelial growth factor (VEGF) and TGF-β, play an important role in receptor glycosylation, which further regulates the sensitivity of receptors to ligands, the effectiveness of signal transduction, and cancer progression [21]. The gene discussed is TGFB1; the disease is cancer.