LncRNA Small Nucleolar RNA host gene 22 (SNHG22) has been found to play a role in the migration and invasion of several carcinomas, such as gastric cancer, hepatocellular carcinoma, and breast cancer.16, 17, 18 However, the contribution of SNHG22 to the biological function of trophoblasts remains unclear. The gene discussed is SNHG22; the disease is gastric cancer.