LncRNA Small Nucleolar RNA host gene 22 (SNHG22) has been found to play a role in the migration and invasion of several carcinomas, such as gastric cancer, hepatocellular carcinoma, and breast cancer.16, 17, 18 However, the contribution of SNHG22 to the biological function of trophoblasts remains unclear. This evidence concerns the gene SNHG22 and breast carcinoma.