This finding suggests that the prevalence of PCV in Caucasian is probably underestimated, therefore in eyes with presumed n-AMD refractory to anti-VEGF monotherapy, high index of suspicion for PCV is needed so prompt PDT can be performed to enable polyp regression and stabilise disease, especially as ICG-A is not performed routinely [8]. Here, VEGFA is linked to age-related macular degeneration.