SOD2 and colorectal carcinoma: The mechanism of study revealed that 4-AAQB could upregulate hsa-mir-324-5p expression and decrease SOD2 expression, which was associated with the simultaneous downregulation of SOD2, N-cadherin, vimentin, c-myc, and bcl-xl2, accompanied by the upregulation of E-cadherin and the bax2 protein, indicating that 4-AAQB played an anticancer role by inhibiting epithelial mesenchymal transformation (EMT) and promoting apoptosis of CRC cells through hsa-mir-324.