It showed that there were great differences in the biochemical and histological findings obtained from the diabetic rats orally receiving STG and those receiving STG–metal complexes, and there was improved insulin secretion of diabetic rats than in the ones given STG only and enhanced antioxidant capacities after the induction of experimental diabetes mellitus in male rats and alleviated complications of diabetic rats than STG alone [5]. The gene discussed is INS; the disease is diabetes mellitus.