Lymphocytopenia, hypocalcemia, low total cholesterol, low total protein levels, and high serum levels of CRP, ferritin, IL-6, procalcitonin, hs-troponin I, LDH, and glucose measured on hospital admission are good predictors of disease severity and may lead to early identification of patients at risk for developing complications, thereby improving optimization and prevention efforts in this cohort. This evidence concerns the gene CRP and lymphopenia.