At the genetic or molecular biology level, Huang Y et al. confirmed that high expression levels of AIB1 (amplified in breast cancer 1) and EIF5A2 (eukaryotic initiation Factor 5A2) were individual predictive factors for bladder recurrence after RNU, and they thought that this information could help urologists to stratify patients to determine those who would benefit from postoperative intravesical chemotherapy [43]. This evidence concerns the gene NCOA3 and breast cancer.