Using the HCC tissue and cirrhosis-only tissue results from the discovery set and the subset of samples in validation set 2 that were labelled at GW (a total of 81 patient samples with H- scores), we calculated a mean H-score of 182.0 ± 57.7 (SD) for TGFBR1 and of 124.6 ± 73.0 for TGFBR2 across diagnostic groups. The gene discussed is TGFBR1; the disease is Cirrhosis.