Neither TGFBR1 nor TGFBR2 had a significant independent contribution to the model for predicting if a patient had cirrhosis only versus HCC: The TGFBR1 adjusted odds ratio (aOR) for cirrhosis versus HCC = 1.006 [95% confidence interval (CI): 0.997–1.016], p = 0.21; TGFBR2 aOR = 1.005 [95% CI: 0.998–1.013], p = 0.16). The gene discussed is TGFBR1; the disease is hepatocellular carcinoma.