As presented in Table 2, the following four factors were independently and significantly associated with increased risk of pneumonitis: anti-PD1 (AOR = 8.32), anti-PDL1 (AOR = 4.10), a higher ECOG score (AOR = 1.71), and squamous cell carcinoma (AOR = 2.91). The gene discussed is PDCD1; the disease is squamous cell carcinoma.