CASP3 and myocardial infarction: Deutsch et al. found that ECFC treatment stimulated robust endogenous angiogenesis in Sca-1+ cardiac progenitors, which was accompanied with an increase in the blood vessels formed following infusion of ECFCs into—ischemic myocardium, while an increase in Sca1+ cardiac-resident progenitors was involved in adverse remodeling after MI (127).