CD4 and cancer: With xCell, we discovered that there was a significant difference in the infiltration of CD8+ T cells, endothelial cells, cancer-associated fibroblasts, hematopoietic stem cells, M2 macrophages, plasmacytoid dendritic cells, and CD4+ Th1 T cells between the high- and low-risk groups, and the high-risk groups had higher stromal and microenvironment scores (Figure 8(a)).