PEG10 expression has been linked to worse prognosis and tumor progression or recurrence in endometrial cancer (Zhang et al., 2021), hepatocellular carcinoma (Bang et al., 2015), oral squamous cell carcinoma (Sharan Singh et al., 2017), showing potential predictive and prognostic ability as a biomarker (Ge et al., 2018). Here, PEG10 is linked to oral cavity squamous cell carcinoma.