NPY and Behcet disease: Although there is limited evidence directly linking PYY to BD, a reduction in peripheral PYY concentrations might underlie the lack of GABA inhibition associated with impaired cognitive function in BD, considering that both neuropeptide Y and γ-aminobutyric acid (GABA) are released by arcuate neuropeptide Y neurons (Acuna-Goycolea et al., 2005; Huber et al., 2018).