High expression of the CD276 gene is thought to be associated with the development and metastasis of several cancers (Yuan et al., 2011; Boland et al., 2013; Mao et al., 2015), and CD70 is involved in the survival of tumor cells and regulatory T cells through interaction with its ligand CD27 (Jacobs et al., 2015). This evidence concerns the gene CD27 and neoplasm.