The top 10 results of the KEGG analysis of DE mRNAs also appeared in Figure 2F, including viral protein interaction with cytokine and cytokine receptor, malaria, complement, and coagulation cascades, rheumatoid arthritis, IL-17 signaling, cytokine-cytokine receptor interaction, TNF signaling pathway, lipid and atherosclerosis, NOD-like receptor signaling and chemokine signaling pathway. This evidence concerns the gene IL17A and rheumatoid arthritis.