ELAVL4 and amyotrophic lateral sclerosis: Several studies have shown that ELAVL4 involved in the pathogenesis of neurodegenerative diseases, such as Alzheimer’s disease (Kang et al., 2014), Parkinson’s disease (Noureddine et al., 2005), and amyotrophic lateral sclerosis (Dell’Orco et al., 2021).