In a recent meta-analysis of more than 13,000 patients [70], the discriminative abilities (area under the receiver operating characteristic curves [AUROCs]) of urinary NGAL were 0.75 (95% confidence interval [CI], 0.73–0.76) and 0.80 (95% CI, 0.79–0.81) for AKI stage 3 and AKI requiring KRT, respectively. Here, LCN2 is linked to acute kidney injury.