A meta-analysis of the included lesions involving at least 300 patients with NF1 (616 in total, some with NF1 features were not reported) showed that pooled and weighted sensitivity, specificity, and AUC values for MRI in detecting MPNSTs were 68%, 93%, and 0.89 when using feature combination, with specificity of perilesional edema and irregular being 94% and 90%, respectively (10).However, it is worth noting that morphological identification based on MRI is highly subjective. Here, NF1 is linked to neurofibromatosis type 1.