Consistent with what has been previously shown in in vivo infection models (25), the in vitro effector protocol generated cells that were CD44+CD62L-, while our optimized, low-avidity memory-inducing protocol mostly generated cells with the lymph node-resident CD44+CD62L+ phenotype (Figures 1C, E, and Supplementary Figure 1) (11). The gene discussed is SELL; the disease is infection.