Plasma levels of M-CSF (84.41 vs. 13.34 mL, p<0.0001), FGF-21 (24.36 vs. 8.64 pg/mL, p<0.001) and GDF-15 (806.82 vs. 430.03 pg/mL, p<0.0001) for breast cancer patients and controls, respectively are shown in Table 3. This evidence concerns the gene GDF15 and breast cancer.