Jahnmatz et al., 2014 compared B cell responses to humoral immunity after a fifth dose of a single component pertussis vaccine (TdAP1, 20 μg PT) versus a five component pertussis vaccine (TdaP5, 2.5 μg PT, 5 μg FHA, 3 μg Prn, and 5 μg Fim2/3). The gene discussed is CIAO3; the disease is pertussis.