Given that a multifaceted condition may affect gastric cancer primed for response to immunotherapy, we analyzed several important factors or potential immunotherapy response biomarkers in relation to the DRGS high and low score groups using TCGA-STAD, including tumor-infiltrating lymphocytes, immune subtypes, TMB, PD-L1 expression and other histologic and molecular classifications (detailed in Results). The gene discussed is CD274; the disease is gastric cancer.