In COPD, EPB41L4A-AS1 was positively correlated with Astrocytes (r = 0.330, p = 0.00004), and MSC (r = 0.2823, p = 0.0005) (Fig. 8D), and INSR was positively correlated with Hepatocytes in COPD (r = 0.5209, p < 0.001; Fig. 8E). The gene discussed is INSR; the disease is chronic obstructive pulmonary disease.