We observed that T cells signalling through o9R (as well as o21R) enriched for a CD62L+ population and higher expression of Fas (CD95) and Sca-1 consistent with a TSCM phenotype, a subset known for its superior anti-tumour activity in adoptive cell therapy (ACT)6,35–37 (Fig. 1d–f). This evidence concerns the gene SELL and neoplasm.