Several deregulated miRNA have been identified in different studies, including the downregulated miR-16, miR-21, miR-26a, miR-29, miR-96, miR-101, miR-146a and miR-155; besides the upregulated miR-135b and miR-17-92 cluster, suggesting that these miRNAs might contribute to ALK-mediated oncogenesis and/or tumor biology [7–11]. This evidence concerns the gene ALK and neoplasm.