To further investigate the influence of CD147 in survival and tumor growth of ALK+ ALCL cells in vivo, KiJK and SUDHL-1 cells with (n = 10; 5 KiJK, 5 SUDHL-1) and without (n = 10; 5 KiJK, 5 SUDHL-1) CD147-KD were subcutaneously implanted in 6–8 weeks old female NOD scid gamma immune deficient mice and analyzed by PET/MRI (Fig. 4A–C). Here, ALK is linked to neoplasm.