TP53 and lung adenocarcinoma: Moreover, they reported that this gene was mutated in lung adenocarcinoma tumor tissue. Furthermore, the magenta module was significantly enriched in five biological pathways, including: "Gap junction assembly", "TP53 Regulates Metabolic Genes","Tandem of pore domain in a weak inwardly rectifying K + channels (TWIK)", "Tight junction interactions", and "Synthesis of 12-eicosatetraenoic acid derivatives".