Interestingly, whereas we could not detect phosphorylated Rab29 in extracts of PBMCs from this cohort, we were able to detect pT71-Rab29 in urinary EVs; and found a significant decrease in pRab29 (normalized to total Rab29) in EVs from A53T-PD patients compared to healthy controls (Fig. 2c). The gene discussed is RAB29; the disease is Parkinson disease.