Considering the major productive rearrangements among Tγδ LGLL cases, we found that the Vγ9-JγP (n = 8/9) and Vδ2-Dδ3-Jδ1 (n = 8/12) usage was the combination most frequently found among the major clones, being nearly exclusive in patients characterized by an indolent clinical course (from #7 to #11, Table 1, Supplementary Tables 1 and 2; Fig. 1a and c). Here, ABCA1 is linked to T-cell large granular lymphocyte leukemia.