In all cases, the GRIA1 variants were identified from clinical or research genetic analysis aimed to determine the genetic cause underlying the individual’s NDD and were found to include four missense variants (c.1906G>A [p.Ala636Thr], c.1880T>C [p.Ile627Thr], c.2234G>A [p.Gly745Asp], and c.1034G>A [p.Arg345Gln]) and one truncating variant (c.1129C>T [p.Arg377Ter]) (Table 1). This evidence concerns the gene GRIA1 and Neurodevelopmental delay.