In contrast to previous studies, we analyzed the relationship between PLAUR expression and degree of immune cell infiltration in ccRCC based on the "CIBERSORT" algorithm, and our results indicated that PLAUR expression was positively correlated with the degree of infiltration of immune cells, such as plasma cells, T cells, M0 macrophages and neutrophils. This evidence concerns the gene PLAUR and nonpapillary renal cell carcinoma.