Compared to that in the shPGAM1‐BC cell lines transfected with siNC, the expression of E‐cadherin in shPGAM1‐BC cell lines transfected with siASS1 was downregulated, whereas the expressions of Snail, Slug, Vimentin, and N‐cadherin were upregulated. The gene discussed is SNAI1; the disease is breast cancer.