Compared to that in the shPGAM1‐BC cell lines transfected with siNC, the expression of E‐cadherin in shPGAM1‐BC cell lines transfected with siASS1 was downregulated, whereas the expressions of Snail, Slug, Vimentin, and N‐cadherin were upregulated. This evidence concerns the gene SNAI2 and breast cancer.