The findings of RT-qPCR and western blotting suggested that inhibition of miR-1205 markedly elevated CCBE1 expression in CRC cell lines (Fig. 5H) and the transfection of miR-1205 inhibitor counteracted the suppressive effect of knocking down circ_0006174 on CCBE1 expression (Fig. 5I). The gene discussed is CCBE1; the disease is colorectal carcinoma.