Similarly, RNA‐Seq analysis of publicly available data comparing human wild‐type (WT) mucosa to CRC samples and analysis comparing intestinal mucosa from wild‐type mice to mucosa from mice with a bi‐allelic deletion of APC revealed a significant induction of RNAPOL1‐related gene sets in CRC and in the APC‐deleted situation (Fig. 1A and Fig. S1B) [8, 21]. The gene discussed is APC; the disease is colorectal carcinoma.