Results showed that overexpressing combined Ccl19/Ccl21a can remarkably retard tumor growth and decrease tumor vitality of hepa1-6 cells, while overexpressing Ccl19 or Ccl21a alone showed a slightly significant difference of tumor growth compared to the control group (Figure S5B-D), indicating that overexpressing combined Ccl19 and Ccl21a elicited a synergistic effect in inhibiting the tumor growth. Here, CCL19 is linked to neoplasm.