MUC1 and neoplasm: The paper presents intriguing in vitro results for cell (co-)staining with five different reporter NPs targeted with either AS1411, MUC1 aptamer or the cyclic arginine-glycine-aspartic acid (cRGDfk) peptide targeting αvβ3 integrin and untargeted beads. In vivo tumor detection was performed analogous to the experiments with gold NP-based SERS reporters to reveal accumulation of AS1411-, MUC1- and cRGDfk-targeted beads in tumors, while no signal was observed for untargeted beads (Figure 4).