FXYD5 and cancer: Additionally, dysadherin OE augmented the myosin IIa phosphorylation at serine 1943 (S1943), indicating an increase in myosin IIa filament dynamics at the leading edge of the cells during cancer cell migration and invasion 44-46, and dysadherin-KO attenuated the myosin IIa phosphorylation (Supplementary Figure S11C).