After BNP treatment plus photo-activation, a high percentage of CD8+ T cells and CD4+ T cells were detected in distant tumors and spleens, and a high rate of mature DCs were detected in the primary tumor and tumor-draining lymph nodes, compared to those upon carrying out other treatments, indicating that photo-activated pyroptosis further induces inspiring antitumor immunity for cancer therapy 120. Here, CD4 is linked to neoplasm.