TNF and asthma: KEGG pathway analysis showed that TNF signaling pathway, HIF-1 signaling pathway, cytokine-cytokine receptor interaction, toll-like receptor signaling pathway, MAPK signaling pathway, etc. were enriched and regulated by BSYQ decoction (Fig. 5A, 5B), indicating the underline comprehensive mechanisms of BSYQ decoction for asthma and IPF treatment.