The strong dependence of NK-cell reactivity on NKG2D-RAE-1γ binding in this setting was revealed by the higher lysis rate for CML-RAE-1γ-Dex groups than for CML-mock-Dex groups (Fig. 2i). The gene discussed is KLRK1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.