However, a correlation between ATAD2 expression and CSCs in lung cancer has not yet been reported.<h4>Methods</h4>The relative messenger RNA (mRNA) levels of ATAD2, CD44, CD133, and hypoxia-inducible factor (HIF)-1α were determined using reverse-transcription quantitative polymerase chain reaction. The gene discussed is PROM1; the disease is lung carcinoma.