CD1D and Autoimmunity: Both LiNKTR1 and B cells isolated from the livers of treated mice could independently protect hosts from adoptive transfer of liver autoimmunity, and systemic αGalCer/CD1d-NP treatment reverted established liver autoimmunity and blunted the progression of beta cell destruction in acutely diabetic mice, without compromising normal immunity or blunting liver-distal autoimmunity.