IFNG and coinfection: Additionally, cells from the BCG-vaccinated and coinfected group secreted significantly more IFN-γ (Supplementary Fig. 3f, g) upon restimulation with PPD at 21 days post Mtb infection than cells from the unvaccinated and coinfected groups, suggesting that the BCG-primed generation of Mtb-specific T cells in the lung might ameliorate the exacerbated pulmonary pathology induced by viral coinfection.