CXCL10 and coinfection: In summary, these data suggest that type II IFN is required for the expression of CXCL9 and CXCL10 in lung infection sites, which play a critical function of Mtb-specific Th1 cell migration from LNs, and that type I IFNs induced by viral coinfection may obstruct this process when type I IFN signal transmission precedes IFN-γ signaling.