PAX8 and cancer: We examined PAX8 expression in 22 different types of cancer using TNMPLOT online software (https://tnmplot.com/analysis/) [11] and found relatively high PAX8 mRNA levels in uterine corpus endometrial carcinoma (UECE), uterine carcinosarcoma (UCS) and ovarian serous cystadenocarcinoma (OSC) (Fig. 1A–C and Supplementary Fig. 1).