Studies in complemented and noncomplemented fibroblasts from 3 FA-A patients showed that genetic correction with FANCA retroviral vectors (+FANCA RVs) reduced NKG2D-L levels when compared with their negative controls (untransduced FA-A cells or cells transduced with a noncorrecting FANCG RV (+FANCG) (Figure 1C). The gene discussed is FANCA; the disease is Fanconi anemia complementation group A.