Maddalena Maddalena A A Biochemical diagnosis of Alzheimer disease by measuring the cerebrospinal fluid ratio of phosphorylated tau protein to beta-amyloid peptide42 Biochemical diagnosis of Alzheimer disease by measuring the cerebrospinal fluid ratio of phosphorylated tau protein to beta-amyloid peptide42 Arch Neurol Arch Neurol 2003 2003 60 60 9 9 1202 1202 1206 1206 10.1001/archneur.60.9.1202 10.1001/archneur.60.9.1202 supplied-pmid 12975284? The gene discussed is MAPT; the disease is early-onset autosomal dominant Alzheimer disease.