We assessed the requirement for Fbxo7 in over 1,000 cell lines by exploring the Cancer Dependency Map (Tsherniak et al., 2017) which provides a large-scale analysis of CRISPR-Cas9 screening data, and uses the Chronos algorithm to calculate a measure of gene knockout fitness (Dempster et al., 2021). Here, FBXO7 is linked to cancer.