The cancers associated with ADH1B rs1229984 were in the head and neck region (Figure 1A), including cancer of the larynx, pharynx, and nasal cavities (OR = 1.68, p = 2.82 × 10−4), cancer of the hypopharynx, (OR = 3.43, p = 2.06 × 10−5) and cancer of the esophagus (OR = 3.80, p = 8.69 × 10−9). This evidence concerns the gene ADH1B and esophageal cancer.