The Flow char for selection of the study population (A), and the PheWAS Manhattan and QQ plots for ADH1B rs1229984 (B) and ALDH2 rs671 (C), respectively Brief Summary Our findings provide evidence of additive and synergic risks of the ADH1B and ALDH2 variants for alcohol‐related disorder and cancer. The gene discussed is ADH1B; the disease is cancer.